Treatment of paediatric vancomycin intoxication: a case report and review of the literature

Notes: “-“ indicates not mentioned in article Therapy: HDF: hemodiafiltration; HD: hemodialysis; CAVH: continuous arteriovenovenous hemofiltration Diagnoses: TF: tibial fracture; POM: polymicrobial osteomyelitis; GD: gastric dysplasia; CD: cardiac disease; VPS: ventriculoperitoneal shunt; PD: Parkinson’s disease; P: pneumonia Vancomycin assay: EMIT: enzyme-multiplied immunoassay technique, Sylva Corp.; FPIA: fluorescence polarization immunoassay, Axsym, Abbott Other medications: PT: piperacillin-tazobactam; Cftx: cefotaxime; TS: trimethoprimsulfamethoxazole Urine output: NO: not oliguric; MO: mildly oliguric; O: oliguric Mechanism of intoxication: PPVT: presumed primary vancomycin toxicity Outcome: TPC: tripling of plasma creatinine from baseline at discharge; DPC: doubling of plasma creatinine from baseline at discharge